Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinololSPAHN-LANGGUTH, H; LANGGUTH, P.European journal of pharmaceutical sciences. 2001, Vol 12, Num 4, pp 361-367, issn 0928-0987Article

Chiral amines derived from 2-arylpropionic acids : novel reagents for the liquid chromatographic (LC) fluorescence assay of optically active carboxylic acid xenobioticsSPAHN, H; LANGGUTH, P.Pharmaceutical research. 1990, Vol 7, Num 12, pp 1262-1268, issn 0724-8741, 7 p.Article

Lipophilisation of hydrophilic compounds: consequences on transepidermal and intestinal transport of trospium chlorideLANGGUTH, P; MUTSCHLER, E.Arzneimittel-Forschung. 1987, Vol 37, Num 12, pp 1362-1366, issn 0004-4172Article

Compound mixtures in Caco-2 cell permeability screens as a means to increase screening capacityTANNERGREN, C; LANGGUTH, P; HOFFMANN, K.-J et al.Pharmazie. 2001, Vol 56, Num 4, pp 337-342, issn 0031-7144Article

Pharmacokinetics of morphine and its surrogates. XI, Effect of simultaneously administered naltrexone and morphine on the pharmacokintetics and pharmacodynamics of each in the dogLANGGUTH, P; KHAN, P. J; GARRETT, E. R et al.Biopharmaceutics & drug disposition. 1990, Vol 11, Num 5, pp 419-444, issn 0142-2782, 26 p.Article

Theme issue: Advances in understanding oral absorption and delivery of problem compoundsLANGGUTH, P; BERMEJO, M; LENNERNÄS, H et al.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, issn 0928-0987, 153 p.Conference Proceedings

The effect of pancreatic and biliary depletion on the in vivo pharmacokinetics of digoxin in pigsTANNERGREN, Christer; EUILEUITCH, Lena; PIERZYNOWSKI, Stefan et al.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, pp 198-204, issn 0928-0987, 7 p.Conference Paper

Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid estersWERDENBERG, D; JOSHI, R; WOLFFRAM, S et al.Biopharmaceutics & drug disposition. 2003, Vol 24, Num 6, pp 259-273, issn 0142-2782, 15 p.Article

Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers : Concentration- and dose-dependent absorption in vitro and in vivoWETTERICH, U; SPAHN-LANGGUTH, H; MUTSCHLER, E et al.Pharmaceutical research. 1996, Vol 13, Num 4, pp 514-522, issn 0724-8741Article

Studies on the stability of aspartame (I) : specific and reproducible HPLC assay for aspartame and its potential degradation products and applications to acid hydrolysis of aspartameLANGGUTH, P; ALDER, R; MERKLE, H. P et al.Pharmazie. 1991, Vol 46, Num 3, pp 188-192, issn 0031-7144, 5 p.Article

Pharmacokinetics of atenolol and metoprolol administered together with piroxicamSPAHN, H; LANGGUTH, P; KRAUSS, D et al.Archiv der Pharmazie (Weinheim). 1987, Vol 320, Num 2, pp 103-107, issn 0365-6233Article

Regulatory aspects of drug dissolution from a European perspectiveGRAFFNER, Christina.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, pp 288-293, issn 0928-0987, 6 p.Conference Paper

Variations of in vitro nitroglycerine permeation through human epidermisLANGGUTH, P; SPAHN, H; MUTSCHLER, E et al.Pharmaceutical research. 1986, Vol 3, Num 1, pp 61-63, issn 0724-8741Article

Pharmacokinetic evaluation of oral fenofibrate nanosuspensions and SLN in comparison to conventional suspensions of micronized drugHANAFY, A; SPAHN-LANGGUTH, H; VERGNAULT, G et al.Advanced drug delivery reviews. 2007, Vol 59, Num 6, pp 419-426, issn 0169-409X, 8 p.Article

Effects of controlled-release on the pharmacokinetics and absorption characteristics of a compound undergoing intestinal efflux in humansTUBIC, Marija; WAGNER, Daniel; SPAHN-LANGGUTH, Hildegard et al.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, pp 231-239, issn 0928-0987, 9 p.Conference Paper

Site of drug absorption after oral administration : Assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tractMASAOKA, Yoshie; TANAKA, Yusuke; KATAOKA, Makoto et al.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, pp 240-250, issn 0928-0987, 11 p.Conference Paper

Variable gastric emptying and discontinuities in drug absorption profiles : dependence of rates and extent of cimetidine absorption on motility phase and pHLANGGUTH, P; LEE, K. M; SPAHN-LANGGUTH, H et al.Biopharmaceutics & drug disposition. 1994, Vol 15, Num 9, pp 719-746, issn 0142-2782Article

Biliary secretion of rosuvastatin and bile acids in humans during the absorption phaseBERGMAN, Ebba; FORSELL, Patrik; TEUELL, Annica et al.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, pp 205-214, issn 0928-0987, 10 p.Conference Paper

Lipid composition effect on permeability across PAMPASEO, Paul R; TEKSIN, Zeynep S; KAO, Joseph P. Y et al.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, pp 259-268, issn 0928-0987, 10 p.Conference Paper

Regional levels of drug transporters along the human intestinal tract : Co-expression of ABC and SLC transporters and comparison with Caco-2 cellsENGLUND, Gunilla; RORSMAN, Fredrik; RÖNNBLOM, Anders et al.European journal of pharmaceutical sciences. 2006, Vol 29, Num 3-4, pp 269-277, issn 0928-0987, 9 p.Conference Paper

Nanosuspension formulations for low-soluble drugs : Pharmacokinetic evaluation using spironolactone as model compoundLANGGUTH, P; HANAFY, A; FRENZEL, D et al.Drug development and industrial pharmacy. 2005, Vol 31, Num 3, pp 319-329, issn 0363-9045, 11 p.Article

P-glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers : The influence of culturing conditions and drug exposure on P-gp expression levelsANDERLE, P; NIEDERER, E; RUBAS, W et al.Journal of pharmaceutical sciences. 1998, Vol 87, Num 6, pp 757-762, issn 0022-3549Article

Structure-permeation relations of Met-enkephalin peptide analogues on absorption and secretion mechanisms in Caco-2 monolayersLANG, V. B; LANGGUTH, P; OTTIGER, C et al.Journal of pharmaceutical sciences. 1997, Vol 86, Num 7, pp 846-853, issn 0022-3549Article

Transport and metabolic pathway of thymocartin (TP4) in excised bovine nasal mucosaLANG, S; LANGGUTH, P; OSCHMANN, R et al.Journal of pharmacy and pharmacology. 1996, Vol 48, Num 11, pp 1190-1196, issn 0022-3573Article

Conventional versus novel conditions for the in vitro dissolution testing of parenteral slow release formulations : application to doxepin parenteral dosage formsGIDO, C; LANGGUTH, P; KREUTER, J et al.Pharmazie. 1993, Vol 48, Num 10, pp 764-769, issn 0031-7144Article